Which of the following best paraphrases the underlined sentence in paragraph 4?

In contrast, insights from various areas makes it difficult to develop a comprehensive approach that unlocks potential for innovation.

In contrast, a comprehensive approach that combines insights from various areas unlocks a huge potential for innovation.

On the other hand, a huge potential for innovation is unlocked when insights from various disciplines are approached with an open mind.

On the other hand, an approach that draws on deep insights from a discipline unlocks a huge potential for innovative solutions.